1.Rate of bioavailability is most
rapid in
A. Solutions ✔️
B. Tablet's
C. Controlled release products
D. Hard gelatine capsules
2. Noyes Whitney equation is related
to
A. Zero order kinetics
B. First order kinetics
C. Pharmacodynamics
D. Dissolution ✔️
3. Which type of bade is required
for antibiotic ointment
A. PEG base
B. Absorption base
C. Hydrocarbon base ✔️
D. None of the above
4. Drugs in suspension and
semi-solid formulation always degrade by
A. Zero order kinetics ✔️
B. First order kinetics
C. Second order kinetics
D. Non-linear kinetics
5. Pacemaker of the heart is
A. AV node
B. SA node ✔️
C. Purkinje node
D. Bundle of his
6. The coeliac ganglion is mainly
A. Sympathetic ✔️
B. Parasympathetic
C. Both sympathetic and
parasympathetic mixed
D. Sensory and motor but not
autonomic
7. Action of parasympathetic system
on Iris musculature is
A. Contraction of Iris
sphincter ✔️
B. Dilatation of Iris sphincter
C. No action on Iris sphincter
D. Effects cannot be predicted
8. Carban dioxide is converted to
bicarbonate by the enzyme
A. Carbonic hydrase
B. Carbonic anhydrase ✔️
C. Bicarbonate synthase
D. None of the above
9. Which of the following is a
Selective Estrogen Receptor Modulator (SERM)
A. Clomiphene
B. Letrozole
C. Tamoxifen ✔️
D. All of the above
10. What will happen if coffee is
taken shortly after cimetidine
A. Duration of effect of caffeine is
reduced
B. Duration of effect of caffeine is
prolonged ✔️
C. There is no change in duration of
effect of caffeine
D. Cannot be predicted
11. Excretion of which drug will be
increased if urine is made more alkaline
A. Procaine
B. Propranolol
C. Phenobarbital ✔️
D. All of the above
12. Which of the drug combinations
are synergistic
A. Ciprofloxacin - Theophylline
B. Probenecid - Penicillin ✔️
C. Penicillin - Aminoglycoside
D. All of the above
13. Effects of taking warfarin along
with aspirin may cause
A. Congestive heart failure
B. Increased bleeding ✔️
C. Kidney damage
D. Liver damage
14. All of the given drug can
decrease the effectiveness of oral contraceptives Except
A. Enalapril ✔️
B. Rifampicin
C. Tetracycline
D. Phenobarbital
15. Anti TB drug which can cause
ototoxicity is
A. Ethambutol
B. Streptomycin ✔️
C. Pyrazinamide
D. Rifampicin
16. Which of the following drugs is
not used in the standard RNTCP regime for MDR-TB
A. Rifampicin ✔️
B. Kanamycin
C. Cycloserine
D. Ofloxacin
17. A malignant condition with
abnormal increase Granulocyte WBC blood will be classifieds as
A. Lymphoid leukemia
B. Myeloid leukemia ✔️
C. Lymphoma
D. All of the above
18. Formalin
contains ________ formaldehyde
A. 27 %
B. 54 %
C. 37 % ✔️
D. None of the above
19. Silver sulfadiazine is used in
management of burn because it high activity against
A. Staphylococcus
B. Pseudomonas ✔️
C. Mycobacterium
D. Corynebacterium
20. Atropine blocks which of the
following neurotransmitter
A. Dopamine
B. Epinephrine
C. Nor epinephrine
D. Acetylcholine ✔️
21. Which is not a side effect
associated with corticosteroid treatment
A. Skeletal muscle weakness
B. Sodium retention
C. Lower resistance to infection
D. Hypoglycemia ✔️
22. Airway obstruction during
anaphylaxis can be best treated
A. Salbutamol
B. Adrenaline ✔️
C. Diphenhydramine
D. Noradrenaline
23. All the following eye drops may
cause a miosis, Except
A. Timolol
B. Neostigmine
C. Atropine ✔️
D. Pilocarpine
24. Greatest absorption of Iron take
place in
A. Duodenum ✔️
B. Descending colon
C. Transverse colon
D. Stomach
25. Safest non opioid analgesic for
ulcer is
A. Celecoxib ✔️
B. Diclofenac sodium
C. Ibuprofen
D. Paracetamol
26. Allopurinol lowers the plasma
concentration of
A. Uric acid ✔️
B. Hypoxanthine
C. Xanthine
D. All of the above
27. In which condition is codeine
used
A. Antidiarroeal
B. Antitussive
C. Analgesic
D. All of the above ✔️
28. Which anti asthamatic is not a
bronchodilator
A. Formoterol
B. Theophylline
C. Sodium cromoglycate ✔️
D. Ipratropium bromide
29. Which one is a centrally acting
skeletal muscle relaxant
A. Carisoprodol ✔️
B. Dantrolene sodium
C. Decamethonium
D. Quinine
30 Which is not a parenteral iron
preparation
A. Iron dextran
B. Iron maltose ✔️
C. Iron carboxymaltose
D. Ferrous sucrose
31. Which of the following is NOT a
proton pump inhibitor
A. Famotidine ✔️
B. Omeprazole
C. Pantoprazole
D. Lansoprazole
32. Action of which antibiotic may
be inhibited by concurrent use of clindamycin
A. Penicillin
B. Erythromycin ✔️
C. Ciprofloxacin
D. All of the above
33. Which vitamin contains cobalt
A. Vitamin B1
B. Vitamin B2
C. Vitamin B6
D. Vitamin B12 ✔️
34. Which drug is not used for
treating acne
A. Benzoyl peroxide
B. Topical clindamycin
C. Monobenzone ✔️
D. Retinoic acid
35. Drying of soft shell capsule is
done by
A. Fluid bed drying
B. Microwave drying
C. Truck drying
D. Vacuum drying ✔️
36. Tablet coating defect is
A. Orange peel effect
B. Sticking
C. Bridging
D. All of the above ✔️
37. Which of the following is a
delayed release system
A. Sugar coated tablet
B. Orally disintegrating tablet
C. Enteric coated tablet ✔️
D. All of the above
38. Lactose is used as
A. Diluent ✔️
B. Glidant
C. Lubricant
D. Disintegrant
39. In sugar coating of tablets,
seal coat is done
A. To prevent moisture
penetration ✔️
B. To round edges
C. To smoothen the surface
D. To prevent breakage
40. Which of the following tablets
is designed to exert local effect in throat
A. Buccal tablets
B. Sublingual tablets
C. Lozenges ✔️
D. Candies
41. Where will Enteric coated
tablets release their medication
A. Oesophagus
B. Small intestines ✔️
C. Stomach
D. Large Intestines
42. Which is a potassium sparing
diuretic
A. Triameterene ✔️
B. Chlorthalidone
C. Acetazolamide
D. Mannitol
43. Which drug may be used for
stimulating uterine contractions
A. Meprobamate
B. Ketoconazole
C. Oxytocin ✔️
D. Metoprolol
44. Which of the following is a
rapidly acting anticoagulant
A. Vitamin K
B. Phenindione
C. Heparin ✔️
D. Warfarin
45. Which of the following is
parasympathomimetic
A. Oxymetazoline
B. Cisapride ✔️
C. Ephedrine
D. All of the above
46. Effect of dopamine on peripheral
circulatory system are
A. Decrease in heart rate and blood
pressure
B. Decrease in heart rate and
increase in BP
C. Increase in heart rate and blood
pressure ✔️
D. No effect on peripheral
circulation
47. Salbutamol is mainly
A. Alpha 1 agonist
B. Beta 1 agonist
C. Beta 2 agonist ✔️
D. All of the above
48. For the calculation of the
volume of Distribution one must take into account
A. Concentration of a substance in
plasma ✔️
B. Concentration of substance in
urine
C. Therapeutical width of drug
action
D. A daily dose of drug
49. Greatest reabsorption of Na+
take place in
A. Ascending loop of Henle
B. Proximal convoluted tubule ✔️
C. Distal tubule
D. Collecting ducts
50. Neurotransmitter at
neuromuscular junction is
A. Serotonin
B. Dopamine
C. Acetylcholine ✔️
D. All of the above
51. Parasympathetic innervation of
heart is through
A. Brachial nerve
B. 3rd and 5th thoracic nerve
C. Trigeminal nerve
D. Vagus nerve ✔️
52. Stimulation of the sympathetic
system will cause
A. Bronchodilation ✔️
B. Brochoconstriction
C. No effect on airways
D. Can't be predicted
53. The Central Drug Laboratory is
located in
A. Delhi
B. Lucknow
C. Kolkata ✔️
D. None of the above
54. Which of the following schedules
to the drug and cosmetics rules refers to requirements for a pharmacy
A. Schedule M
B. Schedule N ✔️
C. Schedule O
D. Schedule P
55. How much lidocaine is present at
a 1:1000 in 30 ml solution
A. 3 gram
B. 300 gm
C. 30 gm ✔️
D. 0.3 mg
56. Normal renal clearance in a
normal adult is
A. 80 ml
B. 100 ml
C. 120 ml ✔️
D. 160 ml
57. Which is a folate antagonist
used in cancer treatment
A. Methotrexate ✔️
B. Cyclosporin
C. Vincristine
D. Tamoxifen
58. Which is not bacteriostatic
antibiotic
A. Chloramphenicol
B. Ampicillin ✔️
C. Tetracycline
D. Sulfadiazine
59. Which is not a treatment for
hypoglycemia
A. Glucagon
B. Glucose
C. Insulin ✔️
D. Fruit juice
60. Which is the major action of
losartan
A. Selective AT1 receptor
antagonist ✔️
B. Selective AT1 receptor antagonist
C. Non selective AT1+AT2 receptor
antagonist
D. AT1 receptor agonist
61. Digoxin is mainly eliminated
through
A. Intestinal elimination
B. Hepatic metabolism
C. Tubular secretion
D. Glomerular filtration ✔️
62. Which antihypertensive drug can
have persistent dry cough as it's side effect
A. Atenolol
B. Enalapril ✔️
C. Methyldopa
D. Diltiazem
63. Na+ Cl" symport in the
early distal convoluted tubule of kidney is inhibited by
A. Thiazides
B. Xipamide
C. Metolazone
D. All of the above ✔️
64. Action of which antibacterial
drug can be augmented by acidifying urine
A. Ciprofloxacin
B. Contrimoxazole
C. Gentamicin
D. Nitrofurantoin ✔️
65. Astringents are compound that
A. Prevent contact of skin with
surroundings
B. Scoothe and soften skin
C. Dissolve intracellular substance
the horny skin layer
D. Precipitate Proteins ✔️
66. Which drug is effective in
psoriasis
A. Resorcinol
B. Tazarotene ✔️
C. Ketoconazole
D. Thymol
67. Albendazole is effective for
A. Roundworm
B. Hookworm
C. Filaria
D. All of the above ✔️
68. Intolerance reaction with
alcohol can occur in patient taking
A. Tetracycline
B. Cimetidine
C. Metronidazole ✔️
D. All of the above
69. Drug of choice for radical curve
of vivax malaria is
A. Primaquine ✔️
B. Chloroquine
C. Quinine
D. ACT
70. In active transport
A. Drug is transported by diffusion
B. The cell membrane forms vesicles
to engulf molecules
C. Transport is against concentration
gradient ✔️
D. There is no energy consumption
71. Which route of drug
administration is likely to lead to the first pass effect
A. Oral ✔️
B. Intravenous
C. Intramuscular
D. Intradermal
72. Half Life of a drug is time
required to
A. Change the amount of drug in
plasma by half during elimination ✔️
B. Metabolize half of the introduced
drug in to active metabolite
C. Absorb half of the introduced
drug
D. Bind half of the introduced drug
to plasma proteins
73. Muscarinic cholinoreceptors are
not found in
A. Gastric glands
B. Respiratory system
C. Skeletal muscle end plate ✔️
D. Heart
74. Bronchodilation produced by
Ipratropium bromide is due to its action as
A. Nicotinic agonist
B. Nicotinic antagonist
C. Muscarinic agonist
D. Muscarinic antagonist ✔️
75. Which of the following inhibits
beta-lactamase enzyme
A. Chloramphenicol
B. Primaquine
C. Sulbactum ✔️
D. Quinine
76. Mannitol is classifieds as
A. Carbonic anhydrase inhibitor
B. Potassium sparing diuretic
C. Loop diuretic
D. Osmotic diuretic ✔️
77. Which of the following may be
used as cheating agent to treat poisoning by heavy metal such as lead or
mercury
A. Dimercaprol ✔️
B. Bismuth subnitrate
C. Sodium phosphate
D. None of the above
78. Which of the following is an
example of the chemical modification of an active pharmaceutical ingredient
A. Mixing a soluble API with water
produce a solution
B. Converting crystalline API in
amorphous form
C. Combining an API with citric acid
to produce the citrate salt ✔️
D. Mixing a poorly soluble API with
water to produce a suspension
79. Which class of drugs can be used
for cleaning the bowel before a surgery
A. Antacid
B. H2 agonists
C. Adsorbents
D. Laxative ✔️
80. Minasipran is a
A. Tricyclic Antidepressant
B. SNRI
C. SSRI ✔️
D. None of the above
81. Which of the following does not
decrease iron absorption
A. Antacids
B. Ascorbic acid ✔️
C. Both A and B
D. Tetracycline
82. Pernicious anemia is caused due
to deficiency of
A. Vitamin B12 ✔️
B. Vitamin B1
C. Copper
D. Iron
83. Lovastatin is a
A. Bile acid sequestrant
B. HMG-CoA reductase inhibitor ✔️
C. Lipoprotein lipase activator
D. Sterol absorption inhibitor
84. Bactericidal action of
cephalosporins is due to
A. Inhibition protein synthesis by
binding to bacterial ribosomes
B. Inhibit protein synthesis by
binding to tRNA
C. Inhibit synthesis of bacterial
cell wall ✔️
D. Distort bacterial gene code
85. Vancomycin is a
A. Lincosamide
B. Aminoglycoside
C. Macrolide
D. Glycopeptide ✔️
86. Prescription drugs are given
under which schedule of drug and cosmetics rules
A. Schedule K
B. Schedule H ✔️
C. Schedule R
D. Schedule M
87. A new Schedule was recently
introduced in the drugs and cosmetics rules for listing carbapenem class lol
and lV generation antibiotics. Which one is it
A. Schedule P1
B. Schedule H1 ✔️
C. Schedule X
D. Schedule Z
88. Which type of cell is involved
in antibody formation
A. Monocyte
B. Neutrophil
C. Plasma cell ✔️
D. Basophil
89. Carbohydrate is stored in human
body mainly as
A. Glucose
B. Glycogen ✔️
C. Starch
D. Inulin
90. Alpha cells in islets of
Langerhans produce
A. Insulin
A. Insulin
B. Glucagon ✔️
C. Somatostatin
D. Secretin
91. β adrenergic blocker that is
primarily eliminated unchanged by renal excretion
A. Propranolol
B. Metoprolol
C. Atenolol ✔️
D. Esmolol
92. High anticholinergic property is
present in the following Antihistaminic
A. Astemizole
B. Diphenhydramine ✔️
C. Terfenadine
D. Cetrizine
93. Patients taking a first
generation H1 Antihistaminic should be advised to avoid
A. Taking milk products
B. Driving motor vehicles ✔️
C. Hard physical exertion
D. All of the above
94. Action for which does of aspirin
required is the lowest
A. Anti platelet aggregation ✔️
B. Anti inflammatory
C. Analgesic
D. Anti pyretic
95. Which is not an adverse effect
seen with Non-Steroidal anti inflammatory drugs
A. Fluid retention
B. Sedation ✔️
C. Gastric irritation
D. Rashes
96. Which is the preferred
penicillin for treatment of syphillis
A. Penicillin V
B. Ampicillin
C. Benzathine Penicillin G ✔️
D. Cloxacillin
97. Which anti TB drug does not
cause liver toxicity
A. Ethambutol ✔️
B. Pyrazinamide
C. Rifampicin
D. Isoniazid
98. Antifungal drug which is
administration only through oral route is
A. Amphotericin B
B. Ketoconazole
C. Griseofulvin ✔️
D. Tolnaftate
99. Characteristic toxicity of
ethambutol is
A. Renal damage
B. Pancreatitis
C. Hepatitis
D. Visual defects ✔️
100. Metronidazole can be used for
A. Hook worm
B. Round worm
C. Giardiasis ✔️
D. Kala azar
