Monday 15 July 2019

ESIC Pharmacist Exam 2014 Solved Question Paper





1. Common side effect of non - Steroidal anti inflammatory drug is _____
A. Sedation
B. Kidney damage
C.Headache
D. Ulceration



2. _______ is a tricyclic Antidepressant drug
A. Amitriptyline
B. Imipramine
C. Phenelzine
D. Triimipramine



3. _________ is Monoamine oxidase inhibitor
A. Imipramine

B. Tranylcypromine
C. Lithium citrate
D. Amitriptyline



4. Parkinson occurs due to _____
A. Depletion of dopamine
B. Excess of dopamine
C. Excess of epinephrine
D. Depletion of epinephrine

5. Mother clove is ______
A. Fruit
B. Stalk
C. Seed
D. Mature flower



6. Cardiac glycoside possess basic nucleus of
A. Tropane
B. Triterpene
C. Quinoline
D. Cyclopenteno phenanthrene



7. Colchicine is commonly known as _______
A. Monkshood
B. Ma Huang
C. Autumn crocus
D. Finger flower



8. Natural fibre gives test for sulphur is _______
A.Wool
B. Cotton
C. Silk
D. Jute



9. _______ leaf is to be dried at 60°C immediately after collection
A. Digitalis
B. Senna
C. Datura
D. Hyoscyamus



10. ____ is a carbohydrate containing drug obtained from Marine source
A. Agar
B. Honey
C. Acacia
D. Ispaghula


11. Dihydrofolate reductase is inhibited by _____
A. Trimethoprim
B. Pyrimethamine

C. Methotrexate
D. All of above


12. _____ is used as an adulterant of Benzoin
A. Myrrh
B. Colophony
C. Asafoetida
D. Balsum


13. _____ is used as a mosquito repellent
A. Punarrnava
B. Hyoscyamus
C. Pyrethrum
D. Ephedra


14. Rifampicin act by
A. Binding with 30S ribosomes
B. Binding with 50S ribosomes
C. Inhibition of DNA dependent RNA polymerase
D. Inhibition of Topoisomerase enzyme


15. Myopia is characterised by one of following
A. Person can see the near objects perfectly
B. Persons find difficulty in seeing the near objects
C. Persons can see the far objects perfectly
D. Persons can see near and far both objects with difficulty


16. ____ is long acting insulin
A. Globulin Zinc insulin
B. Insulin Zinc suspension
C. Protamine Zinc Insulin suspension
D. Isophane Insulin suspension

  
17. Which of the following disease is not spread by mosquito
A.Yellow fever
B. Q fever
C. Filaria
D. Dengue


18. ___ is a Selective β2 receptor blocker
A. Salbutamol
B. Butoxamine
C. Atenolol
D. Dobutamine


19. Xanthine alkaloids acts as
A. β lactamase inhibitor
B. GABA release inhibitor
C. Phosphodiesterase inhibitor
D. 5 - HT releasing agent



20 Which of the following is used in treatment of myasthenia gravis
A. Physostigmine
B. Neostigmine
C. Atropine
D. Diazepam


21. _____ is Selective arterial vasodilator
A. Minoxidil        
B. Diazoxide
C. Hydralazine
D. Losartan


22. _____ is used as anticonvulsant
A. Pentobarbitone
B. Phenobarbitone
C. Cyclobarbitone
D. Barbitone


23. The shoulder of the cylinder of CO2 is painted
A. Blue
B. White
C. Black
D. Grey


24. Which of these substances is used as anticonvulsant
A. Sodium citrate
B. NaCl
C. Sodium peroxide
D. Hydrogen peroxide


25. Which one is used in radiation sterilization
A. X rays
B. β rays
C. γ rays
D. Uv rays


26. Which of the following can be used for counteraction for poisoning caused  
       by organophosphorus compounds
A. Naloxone
B. Pethidine
C. Pralidoxime
D. Charcoal


27. Which one of the following is a genetically determined adverse drug
       reaction
A. Addiction
B. Carcinogenicity
C. Drug induced lupus syndrome
D. Idiosyncrasy


28. Ambulatory patients are
A. Required to admit in the ward for treatment
B. Required to go home after taking treatment in OPD
C. Require emergency treatment
D. None of the above

29. In a drug store, the expiry dated drug formulation are called
A. Scrap items
B. Obsolete items
C. Surplus items
D. Dormant materials


30. Phenobarbitone is
A. Short acting barbiturates
B. Intermediate acting barbiturates
C. Long acting barbiturates
D. None of the above


31. District opium officer appoints  one cultivator as
A. Durg inspector
B.Lambardar
C.Narcotic commissioner
D. Executive commissioner


32. Under which section of indian Penal Code the drug inspector are  
      appointed
A. Section 23
B. Section 22
C. Section 21
D. Section 17



33. Which of the following schedule gives standards mechanical   
       contraceptives
A. Schedule C
B. Schedule D
C. Schedule F
D. Schedule R


34. The Pharmacy Council of India is reconstituted every ____ years
A. 10 years
B. 5 years
C. 2 years
D. 1 year


35. The Ointment base of mineral origin is
A. Olive oil
B. Cottonseed oil
C. Castor oil
D. Paraffin wax


36. Isoniazid induced peripheral neuritis can be prevented by administration
      of
A. Anticonvulsant
B. Anti inflammatory agents
C. Vitamin B6
D. Vitamin B12


37. Which of the following bone have no marrow cavity
A. Scapula
B. Clavicle
C. Ulna
D. None of above


 38. Which of the following is the function of plasma Proteins
A. Regulation of blood volume
B. Regulation of blood pressure
C. Helps in Coagulation process
D. All of the above


39. Diaphragm is a
A. Skeletal muscle
B. Smooth muscle
C. Bone cavity
D. Artery


40. Digitalis is given to the patients suffering from
A. Congestive heart failure
B. Left Ventricle failure
C. Atrial flutter
D. All of above


41. Naloxone is a morphine
A. Agonist
B. Antagonist
C. Mixed agonist and antagonist
D. All of above


42. Colour Index indicate
A. Relative amount of WBC present per cmm of blood
B. Relative amount of haemoglobin present in single RBC
C. Relative amount of haemoglobin present in 100 WBC
D. Relative amount of RBC present per cmm of blood


43. _____ is a major lipid constituent of the cell membrane
A. Phospholipid
B. Glycolipids
C. Cholesterol
D. Fatty acid


44. Clofibrate reduces the
A. Blood pressure
B. Heart rate
C. Elevated triglyceride level
D. Fever


45. Combined Umbelliferone test is positive for ____
A. Nutmeg
B. Asafoetida
C. Tolu balsam
D. Guggul


46. _____ is botanical source of Indian senna
A. Dried leaflets of Cassia angustifolia
B. Dried leaflets of Cassia acutifolia
C. Dried leaflets of Cassia auricularia
D. Dried leaflets of Cassia obovata


47. Which oil is a natural source of Vitamin A
A. Cod liver oil
B. Hydnocarpus
C. Castor oil
D. Shark liver oil


48. Which bark drug is used as cardiotonic
A. Ashoka
B. Cinnamon
C. Arjuna
D. Pterocarpus


49. Keller Killiani test is specified for
A. Anthraquinone glycosides
B. Cardiac glycosides
C. Saponins
D. Flavonoids


50. Tetracycline should not be given with
A. Milk
B. Aluminium hydroxide
C. Beet root
D. All of the above


51. Sodium metal is stored in
A. Well closed container
B. Kerosene
C. Wax
D. Methanol


52. Sodium fluoride is used to cure
A. Inflammation of mouth
B. Bacterial infection
C. Acidity
D. Dental carries


53. _____ is used for treating dandruff
A. Selenium sulphide
B. Sulphur
C. Yellow mercuric oxide
D. Titanium dioxide


54. CO2 is used as
A. Antacid
B. Acidifier
C. Buffer
D. Respiratory stimulant


55. Which of the following conditions is not associated with ischaemic heart
      disease
A. Angina pectoris
B. Hypertension
C. Myocardial infarction
D. Congestive heart disease



56. Mordant black is used as an indicator in the titration of
A. Calcium lactate
B. Sodium acetate
C. Ammonium chloride
D. Hydrogen peroxide


57. The plasticizer used in coating solution is
A. Polyethylene glycol
B. Castor oil
C. Propylene glycol
D. All of the above


58. Which one of the following is used vulcanizing agent for rubber
A. ZnO
B. Sulphur
C. CaCO3
D. Zinc sulphate


59. ______ sterilise talcum powder most effectively
A. Dry heat
B. Autoclaving
C. Gaseous sterilization
D. Freeze drying


60. The formation of wings or ragged extending edges about periphery of the   
       tablet is called
A. Mottling
B. Picking
C. Whiskering
D. Capping


61. The Pharmacy Council of India is constituted by the ____
A. Central government
B. State government
C. Parliament
D. President


62. “Herapathite” is formed in incompatibility of
A. Alkaloidal salt with alkaline substances
B. Alkaloidal salt with soluble barbiturate
C. Alkaloidal salt with soluble iodides
D. Liquorice liquid extract


63. The famous brand “ENO” is an example of
A. Effervescent granules
B. Dry sealed sachets
C. Tablet triturate
D. Powder


64. “Zephiran” is a ______ surfactant
A. Anionic
B. Cationic
C. Non-ionic
D. Ampholytics


65. Butylated hydroxyl toluene is used as
A. an antibacterial
B. an antioxidant
C. a suspending agent
D. a coloring agent


66. Glycerine suppositories containing 92% glycerine are solidified by  
       addition of
A. White wax
B. Stearic acid
C. Sodium stearate
D. PEG 4000


67. Who publish the Indian Pharmacopoeia
A. Central Governor
B. Central Drug Laboratory
C. Ministry of Health and Family welfare
D. Central Indian Pharmacopoeal Laboratory


68. The lead acetate cotton wool is used in the limit test for arsenic to
A. Make the arsine gas
B. Develop the yellow colour
C. Trap the H2S gas
D. None


69. Washing soda is common name for
A. NaHCO3
B. Na2CO3
C. K2CO3
D. NaOH


70. ____is known as Milk of magnesia
A. Suspension of Mg (OH)2
B. Suspension of MgO
C. Suspension of MgCO3
D. Suspension of Milk and MgO