Q. No. 11. Bathochromattic effect mainly occurs due to
Option A Increase in conjugation
Option B Removal of double bonds
Option C Dealkylation
Option D Chromogenic agent
Correct Option A
Q. No. 12.The sample cell commonly used in a flourimeter is
made
of
Option A Quartz
Option B Fused silica
Option C Polystyrene
Option D Glass
Correct Option D
Q. No. 13. The mobile phase used in ion exchange
chromatography is
Option A Polar solvent
Option B Non polar solvent
Option C A mixture of solvent
Option D Buffer solution
Correct Option D
Q. No. 14. Ascorbic acid tablets can be assayed by
Option A Titration with iodine solution
Option B Oxidation involving 2,6-dichloro phenol indophenols
Option C Titration with cerric ammonium sulphate
Option D Titration with sodium hydroxide solution
Correct Option C
Q. No. 15. Which of the following needs to be established
before the search for a lead compound takes place?
Option A The pharmacophore
Option B Structure activity relationship
Option C Bioassay
Option D Patents
Correct Option C
Q. No. 16. Which of the following drugs was not isolated from
a natural source?
Option A Quinine
Option B Morphine
Option C Isoniazid
Option D Artimisinin
Correct Option C
Q. No. 17. What is the term used for drugs that are similar in
structure to a known drug and which are used for
the
same purpose?
Option A 'Copycat' drugs
Option B 'Me-too' drugs
Option C 'Derivative' drugs
Option D 'Analogue' drug
Correct Option B
Q. No. 18. Natural products are often used as lead compounds
in
the design and synthesis of novel drugs. Which of
the
following general characteristics of a natural
product is most likely to be a disadvantage in
synthesising analogues?
Option A Novelty of structure
Option B Complexity of structure
Option C Level of activity
Option D Availability
Correct Option B
Q. No. 19. Which of the following is not an endogenous
compound?
Option A Dopamine
Option B Endorphins
Option C Noradrenaline
Option D Desipramine
Correct Option D
Q. No. 20. Paclitaxel, the potent anticancer drug, was isolated
from which natural source?
Option A The Pacific Yew tree
Option B The Pacific Ocean
Option C A fungus
Option D A bacteria
Correct Option A
